# Release notes: Latest releases
| Major versions | Minor versions |
|---|---|
| v2.9 | v2.9.1, v2.9.1a, v2.9.1b, v2.9.1c, v2.9.2, v2.9.2a, v2.9.2b, v2.9.2c, v2.9.3, v2.9.3a, v2.9.3b, v2.9.3c, v2.9.3d, v2.9.4, v2.9.5, v2.9.6 |
| v2.8 | v2.8.0a, v2.8.0b, v2.8.1, v2.8.2 |
| v2.7 | v2.7.0a, v2.7.1, v2.7.1a, v2.7.2 |
| v2.6 | v2.6.0a, v2.6.0b, v2.6.0c, v2.6.0d, v2.6.0e, v2.6.0f, v2.6.0g |
| v2.5 | |
| v2.4 | v2.4.1 |
# Version 2.9.6
Release date: 28.04.2025
# Data sources
- Add REVEL prediction annotation
- Add AlphaMissense pre-computed variants
# Codebase
- Liftover technical docs
- Bugfix: The current directory may not be writable in a production setting for temp files
# Version 2.9.5
Release date: 21.03.2025
# Data sources
- Clinvar 20250306
# Codebase
- Add hg38 coordinates for small variants
# Version 2.9.4
Release date: 17.02.2025
# Codebase
- Upgrade python from v3.9 to v3.12
# Version 2.9.3d
Release date: 10.02.2025
# Data sources
- VEP v113.3: add back merged cache
# Version 2.9.3c
Release date: 29.01.2025
# Data sources
- Clinvar 20250102
# Version 2.9.3b
Release date: 13.01.2025
# Data sources
- VEP v113.3
# Codebase
- Bugfix: Data packaging fails if the data set key contains hyphens
# Version 2.9.3a
Release date: 22.11.2024
# Data sources
- Clinvar update November 2024
# Version 2.9.3
Release date: 31.10.2024
# Codebase
- Update Pipenv and SeqRepo
- Refactor and document vars dataset property
- Move VCFANNO variables to Dockerfile
- Bug: fixed release notes typo
# Data sources
- Clinvar update October 2024
# Version 2.9.2c
Release date: 16.10.2024
# Data sources
- Clinvar update October 2024
# Version 2.9.2b
Release date: 17.09.2024
# Data sources
- Clinvar update September 2024
# Version 2.9.2a
Release date: 16.08.2024
# Data sources
- Clinvar update August 2024
# Version 2.9.2
Release date: 02.08.2024
# Codebase
- Investigate performance VEP
# Version 2.9.1c
Release date: 10.07.2024
# Data sources
- Clinvar update July 2024
# Version 2.9.1b
Release date: 25.06.2024
# Data sources
- Clinvar update June 2024
# Version 2.9.1a
Release date: 29.05.2024
# Data sources
- Clinvar update May 2024
# Version 2.9.1
Release date: 29.04.2024
# Codebase
- Bug: clinvar XML parser is still broken
- Remove rogue flag
# Data sources
- Clinvar update April 2024
# >> Version 2.9
Release date: 20.03.2024
# Codebase
- Bugfix: VEP110 does not annotate with MANE Select transcript (custom source)
- Bugfix: ClinVar updated their variation archive XML structure
- Add SpliceAI prediction annotation
# Version 2.8.2
Release date 29.02.2024
- Upgrade clinvar 01.02.2024
- Upgrade VEP 110.1
- Use RefSeq only for SNV annotation
- Remove VEP merged cache
# Version 2.8.1
Release date 07.02.2024
- Upgrade vcfanno to 0.3.5
# Version 2.8.0b
Release date: 22.12.2023
# Data sources
- Updated Clinvar to version 20231207.
# Version 2.8.0a
Release date: 24.11.2023
# Data sources
- Updated Clinvar to version 20231102.
# >> Version 2.8
Release date: 20.10.2023
# Data sources
- Updated Clinvar to version 20231005.
- Updated Clinvar to version 20230803.
# Version 2.7.2
Release date: 27.06.2023
# Data sources
- Add VEP RefSeq cache. This enables the VEP
--refseqoption.
# Version 2.7.1a
Release date: 02.06.2023
# Codebase
- Change license from MIT to GNU GPL v3 license.
# Data sources
- Updated Clinvar to version 20230504.
- Update RefSeq GFF to 20220307.
# Version 2.7.1
Release date: 03.05.2023
# Codebase
- Sync data improvements.
# Version 2.7.0a
Release date: 27.04.2023
# Codebase
- Release history documentation update.
- Remove unwanted variables.
- Test release_singularity.
# Data sources
- Updated Clinvar to version 20230406.
# >> Version 2.7
Release date: 23.03.2023
# Codebase
- Errors in configuration parsing are hard to trace.
- Update VEP to 108.2.
- Remove existing rawdata directories when sync_data.py called with
--force.
# Data sources
- Updated Clinvar to version 20230302.
# Version 2.6.0g
Release date: 20.02.2023
# Data sources
- Updated Clinvar to version 20230202.
# Version 2.6.0f
Release date: 24.01.2023
# Codebase
- release history documentation update
# Data sources
- Updated Clinvar to version 20230105.
# Version 2.6.0e
Release date: 30.12.2022
# Codebase
- Release history documentation update
- Correct build command in docs
# Data sources
- Updated Clinvar to version 20221201.
# Version 2.6.0d
Release date: 25.11.2022
# Data sources
- Updated Clinvar to version 20221103.
# Version 2.6.0c
Release date: 18.10.2022
# Data sources
- Updated Clinvar to version 20221006.
# Version 2.6.0b
Release date: 04.10.2022
# Data sources
- Updated Clinvar to version 20220901.
# Version 2.6.0a
Release date: 18.08.2022
# Data sources
- Updated Clinvar to version 20220804.
# >> Version 2.6
Release date: not released
# Codebase
- Update the pipenv lock file
# Data sources
- Updated Clinvar to version 20220707.
# >> Version 2.5
Release date: 20.06.2022
# Codebase
- Show size of annotation data before downloading
# Data sources
- Updated Clinvar to version 20220505.
# Version 2.4.1
Release date: 25.04.2022
# Codebase
- Release history documentation update.
# Data sources
- Updated Clinvar to version 20220407.
# >> Version 2.4
Release date: 18.03.2022
# Codebase
- Generic anno config parser.
# Data sources
- Updated Clinvar to version 20220303.
See older releases for earlier versions.