# Release notes: Latest releases

Major versions Minor versions
v2.6 v2.6.0, v2.6.0a
v2.5 v2.5.0
v2.4 v2.4.1
v2.3 v2.3.1, v2.3.2
v2.2 v2.2.1, v2.2.1a, v2.2.2, v2.2.3, v2.2.4
v2.1 v2.1.1, v2.1.2
v2.0 v2.0.1, v2.0.2, v2.0.3

# Version 2.6.0a

Release date: 18.08.2022

# Data sources

  • Updated Clinvar to version 20220804.

# >> Version 2.6

Release date: not released

# Codebase

  • Update the pipenv lock file

# Data sources

  • Updated Clinvar to version 20220707.

# >> Version 2.5

Release date: 20.06.2022

# Codebase

  • Show size of annotation data before downloading

# Data sources

  • Updated Clinvar to version 20220505.

# Version 2.4.1

Release date: 25.04.2022

# Codebase

  • release history documentation update

# Data sources

  • Updated Clinvar to version 20220407

# >> Version 2.4

Release date: 18.03.2022

# Codebase

  • generic anno config parser

# Data sources

  • Updated Clinvar to version 20220303.

# Version 2.3.2

Release date: 23.02.2022

# Codebase

  • Error log output is truncated in `ops/sync_data.py
  • Trouble with permissions when indexing FASTA in container root folder

# Data sources

  • Updated Clinvar to version 20220203.

# Version 2.3.1

Release date: 12.02.2022

# Codebase

  • Use docker:// when USE_REGISTRY is set
  • Various minor build fixes

# Data sources

  • Updated RefGene to version 20210928.
  • Updated Clinvar to version 20220106.

# >> Version 2.3

Release date: 21.09.2021

# Codebase

  • Moved to Pipenv/Pipfile for dependency management and updating packages.
  • Upgraded Python to v3.9.
  • Upgraded PostgreSQL to version 13.
  • Upgraded Docker base image to Debian 11 (Bullseye).
  • Improvements to code base and dev environment.

# Data sources

  • Upgraded gnomAD to v2.1.1.
  • Upgraded VEP to v104.3.
  • Updated RefSeq to version 20201022.
  • Removed miRNA from RefSeq data to mitigate bug in VEP (opens new window).
  • Upgraded biocommons seqrepo to version 2021-01-29.
  • Updated UTA to version 20210129.
  • Updated ClinVar to version 20210826.

# Version 2.2.4

Release date: 11.06.2021

# Codebase

  • Added force flag to get a clean data folder.

# Version 2.2.3

Release date: 10.06.2021

# Codebase

  • Anno now allows import of empty VCFs.

# Data sources

  • Updated ClinVar to version 20210529.

# Version 2.2.2

Release date: 23.02.2021

# Codebase

  • Minor improvements to backend.

# Data sources

  • Updated ClinVar to version 20210222.

# Version 2.2.1a

Release date: 17.12.2020

# Data sources

  • Updated ClinVar to version 20201203.

# Version 2.2.1

Release date: 15.12.2020

# Codebase

  • Fixed bug where VCFs with ALT variants with missing variants were erroneously set to ..

# >> Version 2.2

Release date: 10.12.2020

# Codebase

  • Moved all code to Python 3.
  • Non-default ports are now allowed for Postgres.

# Data sources

  • Updated UTA to version 20201027 (moved to DigitalOcean and part of datasets.json).

# Version 2.1.2

Release date: 24.11.2020

# Codebase

  • Removed link to sliced VCF.
  • Added proper handling of GATK star alleles (add code to remove star alleles that are conflicting with downstream tools).
  • Fixed issue with PYTHONPATH in Python 3.

# Version 2.1.1

Release date: 16.11.2020

# Codebase

  • Fixed issue with slicing of multiallelic blocks.

# >> Version 2.1

Release date: 23.09.2020

# Codebase

  • Fixed pyrsistent version to 0.15.7 (Python 2 compatible).
  • Moved vt decompose and vt normalize before slicing, to avoid slicing on non-normalized data.
  • Allowed ANNOBUILDER_IMAGE_NAME to be specified.
  • Added CI-test to check datasets.json against DigitalOcean.
  • Fixed remaining issues with duplicates in vcfanno_config.toml.
  • Added license.

# Data sources

  • Updated ClinVar to version 20200907.

# Version 2.0.3

Release date: 13.07.2020

# Codebase

  • Fixed issue with duplicates in vcfanno_config.toml.
  • Added possibility to override envs in Makefile.
  • Added caching for Singularity.

# Data sources

  • Updated ClinVar to version 20200626.

# Version 2.0.2

Release date: 18.05.2020

# Data sources

  • Updated ClinVar to version 20200514.

# Version 2.0.1

Release date: 13.05.2020

# Data sources

  • Added option to set VEP buffer size in annotate.sh and environment variable.

# >> Version 2.0

Release date: 13.05.2020

  • Initial public release.
Last Updated: 8/26/2022, 10:26:45 AM